548 Used Lexus Is-350 for Sale Near Irvine, CA

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lexus
Model: is-350
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2025 Lexus IS 350 350 F SPORT RWD's photo

2025 Lexus IS 350 350 F SPORT RWD

21,045 mi.

14 days on market

JTHGZ1B2XS5086950

$45,888
Good DealSingle owner
Toyota Of Riverside
Riverside, CA
4.6
2024 Lexus IS 350 300 RWD's photo

2024 Lexus IS 350 300 RWD

17,785 mi.

14 days on market

JTHDA1D29R5129661

$39,319
Good DealSingle owner
Cerritos Acura
Cerritos, CA
4.7
2025 Lexus IS 350 350 F SPORT RWD's photo

2025 Lexus IS 350 350 F SPORT RWD

6,101 mi.

14 days on market

JTHGZ1B21S5088702

$49,330
Good DealSingle owner
Newport Lexus
Newport Beach, CA
4.8
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

12,079 mi.

14 days on market

JTHCA1D21P5128223

$42,999
Fair Deal
Cerritos Nissan
Cerritos, CA
4.4

Photos coming soon

2021 Lexus IS 350 300 RWD

14 days on market

JTHCA1D23M5117848

$26,585
Single owner
Claremont Toyota
Claremont, CA
4.4
2022 Lexus IS 350 350 F SPORT RWD's photo

2022 Lexus IS 350 350 F SPORT RWD

66,310 mi.

14 days on market

JTHGZ1B20N5052567

$39,395
Great DealSingle ownerClean title
Nissan Of Tustin
Tustin, CA
4.3
2021 Lexus IS 350 300 RWD's photo

2021 Lexus IS 350 300 RWD

32,035 mi.

14 days on market

JTHCA1D24M5117728

$31,023
Fair DealSingle owner
Stg Montclair
Montclair, CA
4.6
2025 Lexus IS 350 350 F SPORT RWD's photo

2025 Lexus IS 350 350 F SPORT RWD

10,346 mi.

14 days on market

JTHGZ1B27S5092088

$48,992
Good Deal
Autonation Toyota Cerritos
Cerritos, CA
4.5
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

23,501 mi.

14 days on market

JTHDA1D20P5127245

$37,500
Fair Deal
Sunrise Ford North Hollywood
Los Angeles, CA
4.1
2018 Lexus IS 350 300 F SPORT RWD's photo

2018 Lexus IS 350 300 F SPORT RWD

79,620 mi.

14 days on market

JTHBA1D29J5069375

$23,900
Fair Deal
Casey 39 S Cars
Hermosa Beach, CA
2026 Lexus IS 350 350 F SPORT RWD's photo

2026 Lexus IS 350 350 F SPORT RWD

51 mi.

14 days on market

JTHGZ1B29T5100208

$51,075
Good Deal
Lexus Santa Monica
Santa Monica, CA
4.7
2008 Lexus IS 350 250's photo

2008 Lexus IS 350 250

120,043 mi.

14 days on market

JTHBK262285052363

$7,995
Good Deal
Larrys Auto Sales Inc
Fresno, CA
3.8
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

7,942 mi.

15 days on market

JTHDA1D21P5128050

$38,595
Fair DealSingle ownerClean title
Crown Dodge Chrysler Jeep Ram
Ventura, CA
4.0
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

62,652 mi.

15 days on market

JTHGZ1B2XP5065961

$42,490
Great DealSingle ownerClean title
Lexus Of Las Vegas
Las Vegas, NV
4.7
2025 Lexus IS 350 300 F SPORT DESIGN RWD's photo

2025 Lexus IS 350 300 F SPORT DESIGN RWD

13,503 mi.

15 days on market

JTHBA1D24S5133372

$43,493
Good DealSingle owner
Trust Automotive Group
Costa Mesa, CA
1.0
2018 Lexus IS 350 300 F SPORT RWD's photo

2018 Lexus IS 350 300 F SPORT RWD

66,791 mi.

15 days on market

JTHBA1D2XJ5075508

$25,000
Fair Deal
Shmizzys Garage Llc
Los Angeles, CA
5.0
2019 Lexus IS 350 300 F SPORT RWD's photo

2019 Lexus IS 350 300 F SPORT RWD

76,299 mi.

15 days on market

JTHBA1D21K5092862

$24,250
Fair Deal
Puente Hills Mitsubishi
City of Industry, CA
4.2
2015 Lexus IS 350 250 AWD's photo

2015 Lexus IS 350 250 AWD

124,938 mi.

15 days on market

JTHCF1D29F5021243

$18,995
Fair Deal
Winnetka Auto Mall
Los Angeles, CA
3.9
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

51,667 mi.

15 days on market

JTHCA1D20P5123238

$34,888
Good Deal
Crevier Bmw
Santa Ana, CA
4.7
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

25,241 mi.

15 days on market

JTHGZ1B29P5061836

$42,785
Good DealSingle owner
Stg Montclair
Montclair, CA
4.6
2021 Lexus IS 350 350 F SPORT RWD's photo

2021 Lexus IS 350 350 F SPORT RWD

53,687 mi.

15 days on market

JTHGZ1B26M5038025

$39,921
Fair DealSingle owner
Trust Antelope Valley Subaru
Lancaster, CA
4.6
2024 Lexus IS 350 350 F SPORT RWD's photo

2024 Lexus IS 350 350 F SPORT RWD

34,435 mi.

15 days on market

JTHGZ1B21R5074647

$46,990
Fair DealSingle ownerClean title
Lexus Of Las Vegas
Las Vegas, NV
4.7
2007 Lexus IS 350 250 6AT's photo

2007 Lexus IS 350 250 6AT

62,100 mi.

15 days on market

JTHBK262475034073

$15,250
Fair Deal
Zeus Auto Dealers
Brea, CA
2008 Lexus IS 350 250's photo

2008 Lexus IS 350 250

109,812 mi.

15 days on market

JTHBK262X85084865

$11,922
Fair DealSingle ownerClean title
South Bay Lexus
Torrance, CA
4.8
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

14,676 mi.

16 days on market

JTHCA1D21P5127427

$39,635
Fair Deal
Lexus Santa Monica
Santa Monica, CA
4.7
2014 Lexus IS 350 250 6AT's photo

2014 Lexus IS 350 250 6AT

156,878 mi.

16 days on market

JTHBF1D21E5030352

$15,499
Fair Deal
Salas Auto Group
Indio, CA
4.4
2024 Lexus IS 350 350 F SPORT AWD's photo

2024 Lexus IS 350 350 F SPORT AWD

35,696 mi.

16 days on market

JTHGZ1E29R5033985

$49,922
Lexus Of Riverside
Riverside, CA
4.7
2014 Lexus IS 350 250 6AT's photo

2014 Lexus IS 350 250 6AT

127,021 mi.

16 days on market

JTHBF1D22E5031123

$13,950
Good Deal
Johnnys Motors Inc
Fontana, CA
3.6
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Find Used Lexus IS 350 in Irvine, CA

In the U.S., the Lexus IS 350 is available as Convertible, Sedan, and Wagon. The best choice typically depends on space needs and personal preference.