589 Used Lexus Is-350 for Sale Near Lancaster, CA

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Model: is-350
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2007 Lexus IS 350 250 AWD's photo

2007 Lexus IS 350 250 AWD

159,571 mi.

49 days on market

JTHCK262172017866

$5,999
Premier Auto Works Alsip
Alsip, IL
2008 Lexus IS 350 250 6AT's photo

2008 Lexus IS 350 250 6AT

123,546 mi.

1740 days on market

JTHBK262582077534

$13,995
Quantum Auto Sales Inc
Garden Grove, CA
4.8
2014 Lexus IS 350 250 6AT's photo

2014 Lexus IS 350 250 6AT

138,768 mi.

46 days on market

JTHBF1D2XE5005997

$13,995
Good Deal
H R Auto Sales Llc
Somerton, AZ
3.7
2024 Lexus IS 350 300 RWD's photo

2024 Lexus IS 350 300 RWD

5,926 mi.

4 days on market

JTHBA1D21R5132156

$42,999
Fair DealSingle ownerClean title
Shottenkirk Desert Lexus
Cathedral City, CA
4.0
2025 Lexus IS 350 350 F SPORT RWD's photo

2025 Lexus IS 350 350 F SPORT RWD

5,616 mi.

4 days on market

JTHGZ1B23S5088720

$51,999
Fair DealSingle ownerClean title
Shottenkirk Desert Lexus
Cathedral City, CA
4.0

Photos coming soon

2015 Lexus IS 350 250

100,454 mi.

4 days on market

JTHBF1D29F5077467

$19,995
Fair Deal
Us Auto Sales Group
Las Vegas, NV
4.7
2020 Lexus IS 350 300 F SPORT BLACK LINE RWD's photo

2020 Lexus IS 350 300 F SPORT BLACK LINE RWD

72,206 mi.

5 days on market

JTHGA1D29L5106384

$29,922
Fair Deal
Lexus Of Riverside
Riverside, CA
4.7
2018 Lexus IS 350 300 F SPORT RWD's photo

2018 Lexus IS 350 300 F SPORT RWD

71,940 mi.

5 days on market

JTHBA1D27J5068810

$21,995
Good Deal
A R Motorcars Llc
San Bernardino, CA
5.0
2015 Lexus IS 350 250's photo

2015 Lexus IS 350 250

88,698 mi.

5 days on market

JTHBF1D24F5082978

$19,371
Fair Deal
South County Lexus
Mission Viejo, CA
4.6
2022 Lexus IS 350 300 RWD's photo

2022 Lexus IS 350 300 RWD

63,062 mi.

5 days on market

JTHDA1D23N5118293

$32,449
Good Deal
Toyota Of Lancaster
Lancaster, CA
4.2
2016 Lexus IS 350 200t's photo

2016 Lexus IS 350 200t

133,344 mi.

5 days on market

JTHBA1D22G5022097

$16,995
Good Deal
Cartime
Ontario, CA
4.7
2024 Lexus IS 350 300 RWD's photo

2024 Lexus IS 350 300 RWD

37,326 mi.

5 days on market

JTHBA1D25R5132080

$38,985
Great DealSingle ownerClean title
Sedano Chevrolet
Santee, CA
4.8
2021 Lexus IS 350 300 RWD's photo

2021 Lexus IS 350 300 RWD

125,249 mi.

5 days on market

JTHCA1D29M5115778

$22,888
Great DealClean title
Puente Hills Toyota
City of Industry, CA
4.5
2018 Lexus IS 350 300 RWD's photo

2018 Lexus IS 350 300 RWD

67,257 mi.

5 days on market

JTHBA1D23J5062017

$24,295
Fair DealSingle owner
Tim Moran Ford
Hemet, CA
4.8
2025 Lexus IS 350 350 F SPORT AWD's photo

2025 Lexus IS 350 350 F SPORT AWD

29,844 mi.

5 days on market

JTHGZ1E23S5040517

$56,084
Lexus Santa Monica
Santa Monica, CA
4.7
2025 Lexus IS 350 350 F SPORT RWD's photo

2025 Lexus IS 350 350 F SPORT RWD

24,489 mi.

5 days on market

JTHGZ1B2XS5085071

$46,635
Good Deal
Lexus Santa Monica
Santa Monica, CA
4.7
2024 Lexus IS 350 350 F SPORT RWD's photo

2024 Lexus IS 350 350 F SPORT RWD

29,769 mi.

5 days on market

JTHGZ1B23R5079252

$42,988
Great DealSingle owner
Wilson Automotive Group
Orange, CA
4.0
2018 Lexus IS 350 350 F SPORT RWD's photo

2018 Lexus IS 350 350 F SPORT RWD

52,450 mi.

5 days on market

JTHBZ1D22J5032595

$33,764
Fair Deal
Lexus Of Thousand Oaks
Thousand Oaks, CA
4.6
2014 Lexus IS 350 250 6AT's photo

2014 Lexus IS 350 250 6AT

98,351 mi.

5 days on market

JTHBF1D23E5021474

$17,073
Fair Deal
Audi Pasadena
Pasadena, CA
4.8
2017 Lexus IS 350 200t's photo

2017 Lexus IS 350 200t

19,701 mi.

5 days on market

JTHBA1D25H5046184

$26,721
Fair Deal
South County Lexus
Mission Viejo, CA
4.6
2010 Lexus IS 350 250 6AT's photo

2010 Lexus IS 350 250 6AT

122,967 mi.

5 days on market

JTHBF5C29A2098399

Contact Dealer
Crown Lexus
Ontario, CA
4.6
2014 Lexus IS 350 350C's photo

2014 Lexus IS 350 350C

147,678 mi.

5 days on market

JTHFE2C27E2510165

$14,995
Good Deal
Zee Motors
Buena Park, CA
4.8
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

49,141 mi.

5 days on market

JTHDA1D21P5128176

$32,999
Good Deal
Car Star Motors
Los Angeles, CA
4.1
2014 Lexus IS 350 250 6AT's photo

2014 Lexus IS 350 250 6AT

159,135 mi.

5 days on market

JTHBF1D25E5032248

$14,084
Good Deal
Dealers Choice Iv Porterville
Porterville, CA
4.9
2013 Lexus IS 350 350's photo

2013 Lexus IS 350 350

134,521 mi.

5 days on market

JTHBE5C28D5031525

$17,888
Carco Sales Finance
Chula Vista, CA
4.8
2022 Lexus IS 350 350 F SPORT RWD's photo

2022 Lexus IS 350 350 F SPORT RWD

33,479 mi.

5 days on market

JTHSZ1B23N5053092

$44,997
Fair DealSingle owner
K S Acura Of Kearny Mesa
San Diego, CA
4.8
2017 Lexus IS 350 200t's photo

2017 Lexus IS 350 200t

103,770 mi.

6 days on market

JTHBA1D25H5050445

$19,203
Good DealSingle owner
Cardinaleway Mazda Corona
Corona, CA
4.2
2025 Lexus IS 350 300 F SPORT DESIGN RWD's photo

2025 Lexus IS 350 300 F SPORT DESIGN RWD

11,581 mi.

6 days on market

JTHBA1D29S5135179

$43,988
Good Deal
Mercedes Benz Of West Covina
West Covina, CA
3.4
2011 Lexus IS 350 F's photo

2011 Lexus IS 350 F

102,944 mi.

6 days on market

JTHBP5C21B5008160

$34,989
Good Deal
Autobakers
Los Angeles, CA
4.3
2024 Lexus IS 350 350 F SPORT RWD's photo

2024 Lexus IS 350 350 F SPORT RWD

17,446 mi.

6 days on market

JTHGZ1B28R5080526

$43,995
Great DealSingle owner
Pacific Auto Center
Fontana, CA
4.4
2014 Lexus IS 350 250 6AT's photo

2014 Lexus IS 350 250 6AT

111,482 mi.

6 days on market

JTHBF1D23E5040378

$16,498
Fair Deal
Laguna Niguel Gmc
Laguna Niguel, CA
4.5
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Find Used Lexus IS 350 in Lancaster, CA

In the U.S., the Lexus IS 350 is available as Convertible, Sedan, and Wagon. The best choice typically depends on space needs and personal preference.