Explore 530 Used Lexus Is-350 Listings Near Roanoke, VA

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lexus
Model: is-350
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2024 Lexus IS 350 350 F SPORT RWD's photo

2024 Lexus IS 350 350 F SPORT RWD

14,715 mi.

57 days on market

JTHBZ1B24R5082106

$45,990
Great Deal
Autoplex Atlanta
Duluth, GA
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

28,937 mi.

22 days on market

JTHGZ1B27P5068879

$44,550
Impex Auto Sales
Greensboro, NC
4.8
2015 Lexus IS 350 350 AWD's photo

2015 Lexus IS 350 350 AWD

131,280 mi.

455 days on market

JTHCE1D28F5008163

$18,995
Good Deal
Momentum Motor Group
Lancaster, SC
3.8
2011 Lexus IS 350 250C 6ECTi's photo

2011 Lexus IS 350 250C 6ECTi

103,660 mi.

3 days on market

JTHFF2C29B2521080

$16,997
Fair Deal
The Auto Finders
Durham, NC
4.6
2012 Lexus IS 350 250 AWD's photo

2012 Lexus IS 350 250 AWD

202,638 mi.

15 days on market

JTHCF5C25C5055443

$6,786
Virginia Auto Mall
Woodford, VA
3.9
2017 Lexus IS 350 200t's photo

2017 Lexus IS 350 200t

86,745 mi.

17 days on market

JTHBA1D22H5040441

$15,495
Best Buy Auto Group
Fredericksburg, VA
5.0
2010 Lexus IS 350 250 AWD's photo

2010 Lexus IS 350 250 AWD

120,378 mi.

27 days on market

JTHCF5C28A5039430

$9,995
Good Deal
Best Value Autos
Spotsylvania Courthouse, VA
4.2
2024 Lexus IS 350 350 F SPORT RWD's photo

2024 Lexus IS 350 350 F SPORT RWD

19,336 mi.

29 days on market

JTHGZ1B2XR5074808

$45,890
Impex Auto Sales
Greensboro, NC
4.8
2012 Lexus IS 350 350 AWD's photo

2012 Lexus IS 350 350 AWD

92,108 mi.

51 days on market

JTHCE5C24C5002428

$14,495
Vanguard Automotive
Chantilly, VA
4.7
2014 Lexus IS 350 250 6AT's photo

2014 Lexus IS 350 250 6AT

125,320 mi.

471 days on market

JTHBF1D27E5006718

$14,995
Good Deal
Momentum Motor Group
Lancaster, SC
3.8
2012 Lexus IS 350 250 AWD's photo

2012 Lexus IS 350 250 AWD

146,779 mi.

1436 days on market

JTHCF5C29C5060127

$8,997
Great DealClean title
Mbl Auto Trucks
Woodford, VA
3.4
New listing
2025 Lexus IS 350 350 F SPORT DESIGN RWD's photo

2025 Lexus IS 350 350 F SPORT DESIGN RWD

7,823 mi.

1 day on market

JTHBZ1B23S5090204

$50,399
Fair Deal
Fred Anderson Honda
Greenville, SC
4.5
New listing
2018 Lexus IS 350 350 F SPORT AWD's photo

2018 Lexus IS 350 350 F SPORT AWD

93,369 mi.

1 day on market

JTHCZ1D28J5015966

$27,394
Fair Deal
Ourisman Fairfax Toyota
Fairfax, VA
4.5
New listing
2025 Lexus IS 350 350 F SPORT RWD's photo

2025 Lexus IS 350 350 F SPORT RWD

5,520 mi.

1 day on market

JTHGZ1B28S5084971

$49,903
Good DealSingle owner
Sheehy Lexus Of Annapolis
Annapolis, MD
4.8
New listing
2016 Lexus IS 350 300 AWD's photo

2016 Lexus IS 350 300 AWD

138,548 mi.

1 day on market

JTHCM1D26G5005623

Contact Dealer
Damas Auto Llc
Chantilly, VA
4.6
New listing
2007 Lexus IS 350 250 AWD's photo

2007 Lexus IS 350 250 AWD

112,453 mi.

1 day on market

JTHCK262475015107

$8,750
Fair Deal
Drive Prime Motors
Fredericksburg, VA
4.5
New listing
2022 Lexus IS 350 350 F SPORT AWD's photo

2022 Lexus IS 350 350 F SPORT AWD

30,499 mi.

1 day on market

JTHGZ1E29N5026464

$43,754
Fair Deal
Lexus Of North Hills
Wexford, PA
4.8
New listing
2024 Lexus IS 350 350 F SPORT AWD's photo

2024 Lexus IS 350 350 F SPORT AWD

20,881 mi.

1 day on market

JTHGZ1E21R5036153

$48,395
Fair Deal
Vann York Toyota
High Point, NC
4.6
New listing
2011 Lexus IS 350's photo

2011 Lexus IS 350

95,726 mi.

1 day on market

JTHFF2C29B2519359

$17,999
Annapolis Hyundai
Edgewater, MD
4.5
New listing
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

75,946 mi.

1 day on market

JTHGZ1B21P5060499

$38,900
Good Deal
Hyundai Of Greenville
Greenville, SC
4.3
New listing
2016 Lexus IS 350 300 AWD's photo

2016 Lexus IS 350 300 AWD

114,862 mi.

1 day on market

JTHCM1D23G5012691

$16,995
Good Deal
Auto Buying Service
Fairfax, VA
4.7
New listing
2008 Lexus IS 350 250 AWD's photo

2008 Lexus IS 350 250 AWD

162,000 mi.

1 day on market

JTHCK262282027016

$6,999
Good Deal
Brothers Auto Sales
Virginia Beach, VA
4.5
New listing
2024 Lexus IS 350 350 F SPORT RWD's photo

2024 Lexus IS 350 350 F SPORT RWD

7,407 mi.

1 day on market

JTHGZ1B22R5081445

$53,729
Fair Deal
Flow Lexus Of Greensboro
Greensboro, NC
4.7
2022 Lexus IS 350 350 F SPORT RWD's photo

2022 Lexus IS 350 350 F SPORT RWD

24,309 mi.

2 days on market

JTHGZ1B26N5052315

$44,849
Fair DealClean title
Lugoff Toyota
Lugoff, SC
4.8

Photos coming soon

2015 Lexus IS 350 250

138,013 mi.

2 days on market

JTHBF1D25F5058866

Contact Dealer
Single owner
Vip Kars Inc
Fayetteville, NC
3.9
2014 Lexus IS 350 350's photo

2014 Lexus IS 350 350

168,443 mi.

2 days on market

JTHBE1D26E5003571

$13,995
Good Deal
Car Connect
Stafford, VA
5.0
2015 Lexus IS 350 350 AWD's photo

2015 Lexus IS 350 350 AWD

99,122 mi.

2 days on market

JTHCE1D21F5008439

$25,995
Fair Deal
Panda Autos
Vienna, VA
4.7
2014 Lexus IS 350 250 AWD's photo

2014 Lexus IS 350 250 AWD

97,119 mi.

2 days on market

JTHCF1D23E5000256

$17,880
Fair Deal
Lindsay Lexus Of Alexandria
Alexandria, VA
4.9
2024 Lexus IS 350 350 F SPORT DESIGN RWD's photo

2024 Lexus IS 350 350 F SPORT DESIGN RWD

33,223 mi.

2 days on market

JTHBZ1B26R5076761

$42,600
Good DealSingle owner
Scott Clark Honda
Charlotte, NC
4.6
2013 Lexus IS 350 250 AWD's photo

2013 Lexus IS 350 250 AWD

116,071 mi.

2 days on market

JTHCF5C21D5063282

$14,990
Fair Deal
Intouch Auto Outlet
Spotsylvania Courthouse, VA
4.7
2024 Lexus IS 350 350 F SPORT RWD's photo

2024 Lexus IS 350 350 F SPORT RWD

17,054 mi.

2 days on market

JTHGZ1B25R5081567

$46,900
Fair Deal
Safford Brown Mazda Fairfax
Fairfax, VA
4.5
2009 Lexus IS 350 250 AWD's photo

2009 Lexus IS 350 250 AWD

154,883 mi.

2 days on market

JTHCK262695029416

$6,000
Great Deal
Garcias Used Auto Sales Llc
Fayetteville, NC
4.6
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Find Used Lexus IS 350 in Roanoke, VA

In the U.S., the Lexus IS 350 is available as Convertible, Sedan, and Wagon. The best choice typically depends on space needs and personal preference.