Explore 155 Used Lexus Is-350 Listings Near Saint Charles, MO

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Model: is-350
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2024 Lexus IS 350 350 F SPORT RWD's photo

2024 Lexus IS 350 350 F SPORT RWD

19,336 mi.

26 days on market

JTHGZ1B2XR5074808

$45,890
Impex Auto Sales
Greensboro, NC
2008 Lexus IS 350 250 AWD's photo

2008 Lexus IS 350 250 AWD

178,972 mi.

14 days on market

JTHCK262082026012

$5,999
Premier Auto Works Alsip
Alsip, IL
4.6
2016 Lexus IS 350 300 AWD's photo

2016 Lexus IS 350 300 AWD

126,686 mi.

19 days on market

JTHCM1D22G5006266

$16,995
Good Deal
Frankfort Car Outlet
Frankfort, IL
4.5
2019 Lexus IS 350 300 F SPORT RWD's photo

2019 Lexus IS 350 300 F SPORT RWD

71,482 mi.

37 days on market

JTHBA1D28K5084824

$27,995
Fair Deal
Highend Motors
Chicago, IL
4.3
2012 Lexus IS 350 250 AWD's photo

2012 Lexus IS 350 250 AWD

195,414 mi.

5 days on market

JTHCF5C21C5055844

$8,995
Good Deal
Charlies Choice Cars
Saint Charles, MO
4.6
2007 Lexus IS 350 250 AWD's photo

2007 Lexus IS 350 250 AWD

159,571 mi.

29 days on market

JTHCK262172017866

$5,999
Premier Auto Works Alsip
Alsip, IL
4.6
2022 Lexus IS 350 350 F SPORT RWD's photo

2022 Lexus IS 350 350 F SPORT RWD

40,702 mi.

37 days on market

JTHGZ1B23N5057309

$43,995
Fair Deal
Motor Cars Of Chicago
Joliet, IL
4.8
2016 Lexus IS 350 200t's photo

2016 Lexus IS 350 200t

132,848 mi.

39 days on market

JTHBA1D29G5004647

$16,995
Good Deal
Highend Motors
Chicago, IL
4.3
2022 Lexus IS 350 350 F SPORT AWD's photo

2022 Lexus IS 350 350 F SPORT AWD

40,262 mi.

42 days on market

JTHGZ1E21N5026216

$41,649
Guaranteed Motor Cars
Lansing, IL
4.8
2015 Lexus IS 350 250 AWD's photo

2015 Lexus IS 350 250 AWD

136,186 mi.

42 days on market

JTHCF1D27F5021306

$14,995
Twin City Auto Mall
Bloomington, IL
4.5
2016 Lexus IS 350 300 AWD's photo

2016 Lexus IS 350 300 AWD

75,105 mi.

91 days on market

JTHCM1D28G5005879

$18,995
Good Deal
Frankfort Car Outlet
Frankfort, IL
4.5
2010 Lexus IS 350 250C 6ECTi's photo

2010 Lexus IS 350 250C 6ECTi

152,233 mi.

147 days on market

JTHFF2C27A2501411

$8,490
Good Deal
Auto Deals
Roselle, IL
4.6
2008 Lexus IS 350 250 6AT's photo

2008 Lexus IS 350 250 6AT

134,735 mi.

250 days on market

JTHBK262185073950

$5,990
Luxury Automaxx
Tinley Park, IL
4.5
2018 Lexus IS 350 300 AWD's photo

2018 Lexus IS 350 300 AWD

61,366 mi.

2 days on market

JTHC81D22J5027145

Contact Dealer
Jsj Auto Sales Llc
Grain Valley, MO
4.8
2022 Lexus IS 350 300 AWD's photo

2022 Lexus IS 350 300 AWD

49,478 mi.

2 days on market

JTHC81F26N5049037

Contact Dealer
Single owner
Mcgrath Lexus Of Westmont
Westmont, IL
4.7
2015 Lexus IS 350 250's photo

2015 Lexus IS 350 250

125,896 mi.

2 days on market

JTHBF1D29F5060667

$16,900
Fair Deal
Pristine Auto Line Llc
Springfield, MO
4.9
2012 Lexus IS 350 250 AWD's photo

2012 Lexus IS 350 250 AWD

217,375 mi.

2 days on market

JTHCF5C25C5056334

$8,999
Good Deal
Jones Family Motors Llc
Plattsburg, MO
4.8
2021 Lexus IS 350 300 RWD's photo

2021 Lexus IS 350 300 RWD

50,127 mi.

3 days on market

JTHAA1D22M5113832

$30,990
Fair Deal
Jim Trenary Troy
Troy, MO
4.1
2015 Lexus IS 350 350 AWD's photo

2015 Lexus IS 350 350 AWD

99,596 mi.

3 days on market

JTHCE1D26F5009473

Contact Dealer
Orland Toyota
Tinley Park, IL
4.4
2008 Lexus IS 350 250 AWD's photo

2008 Lexus IS 350 250 AWD

146,268 mi.

3 days on market

JTHCK262385016489

$7,490
Good Deal
Car Tastic
Villa Park, IL
5.0
2016 Lexus IS 350 300 AWD's photo

2016 Lexus IS 350 300 AWD

46,664 mi.

3 days on market

JTHCM1D24G5008696

$24,999
Fair Deal
Lexus Of Peoria
Peoria, IL
4.8
2019 Lexus IS 350 300 F SPORT AWD's photo

2019 Lexus IS 350 300 F SPORT AWD

110,934 mi.

3 days on market

JTHC81D29K5034529

$21,476
Good Deal
Indy Luxury Motorsports
Indianapolis, IN
4.2
2020 Lexus IS 350 350 F SPORT BLACK LINE AWD's photo

2020 Lexus IS 350 350 F SPORT BLACK LINE AWD

65,057 mi.

3 days on market

JTHGZ1E28L5018319

$32,977
Fair Deal
Castle Mazda Downers Grove
Downers Grove, IL
4.3
2024 Lexus IS 350 350 F SPORT AWD's photo

2024 Lexus IS 350 350 F SPORT AWD

23,577 mi.

4 days on market

JTHGZ1E20R5034815

$53,988
Single owner
Mcgrath Lexus Of Westmont
Westmont, IL
4.7
2006 Lexus IS 350 250 AWD's photo

2006 Lexus IS 350 250 AWD

130,739 mi.

4 days on market

JTHCK262762005994

$7,995
Fair DealClean title
Car Union Of Kansas City
Kansas City, MO
4.9
2006 Lexus IS 350 350's photo

2006 Lexus IS 350 350

125,926 mi.

4 days on market

JTHBE262165007919

$12,593
Fair Deal
Hendrick Lexus Kansas City
Merriam, KS
4.9
2018 Lexus IS 350 300 AWD's photo

2018 Lexus IS 350 300 AWD

90,625 mi.

5 days on market

JTHC81D26J5029500

$23,541
Fair Deal
Hendrick Lexus Kansas City
Merriam, KS
4.9
2019 Lexus IS 350 300 RWD's photo

2019 Lexus IS 350 300 RWD

77,850 mi.

6 days on market

JTHBA1D25K5087759

$24,305
Fair Deal
American Auto Outlet
Nixa, MO
4.7
2025 Lexus IS 350 350 F SPORT DESIGN AWD's photo

2025 Lexus IS 350 350 F SPORT DESIGN AWD

7,930 mi.

6 days on market

JTHBZ1E29S5042301

$48,999
Fair Deal
Lexus Of Peoria
Peoria, IL
4.8
2010 Lexus IS 350 250 AWD's photo

2010 Lexus IS 350 250 AWD

154,533 mi.

6 days on market

JTHCF5C20A5041964

$7,990
Good Deal
Nb Motors
Naperville, IL
2021 Lexus IS 350 300 AWD's photo

2021 Lexus IS 350 300 AWD

35,331 mi.

6 days on market

JTHC81F23M5044912

$36,393
Fair Deal
Hendrick Lexus Kansas City
Merriam, KS
4.9
2016 Lexus IS 350 350 AWD's photo

2016 Lexus IS 350 350 AWD

84,470 mi.

6 days on market

JTHCE1D23G5012686

$25,096
Fair Deal
Car City Wholesale
Shawnee, KS
4.8
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Find Used Lexus IS 350 in Saint Charles, MO

In the U.S., the Lexus IS 350 is available as Convertible, Sedan, and Wagon. The best choice typically depends on space needs and personal preference.