525 Used Lexus Is-350 for Sale Near Santee, CA

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lexus
Model: is-350
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2012 Lexus IS 350 250 6AT's photo

2012 Lexus IS 350 250 6AT

93,670 mi.

5 days on market

JTHBF5C20C5179423

$12,995
Romcar
Commerce, CA
2026 Lexus IS 350 350 F SPORT DESIGN RWD's photo

2026 Lexus IS 350 350 F SPORT DESIGN RWD

656 mi.

6 days on market

JTHBZ1B27T5099134

$50,080
Good DealSingle ownerClean title
Lexus Of Oxnard
Oxnard, CA
4.7
2012 Lexus IS 350 250 6AT's photo

2012 Lexus IS 350 250 6AT

146,980 mi.

6 days on market

JTHBF5C25C5180664

$10,988
Good DealSingle owner
Toyota Of Huntington Beach
Huntington Beach, CA
4.5
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

30,236 mi.

6 days on market

JTHGZ1B28P5069166

$45,912
Fair Deal
Tustin Lexus
Tustin, CA
4.6
2019 Lexus IS 350 300 RWD's photo

2019 Lexus IS 350 300 RWD

50,912 mi.

6 days on market

JTHBA1D29K5098960

$28,979
Fair Deal
Audi Fletcher Jones
Costa Mesa, CA
4.0
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

10,682 mi.

6 days on market

JTHDA1D2XP5124790

$40,888
Fair Deal
Longo Lexus
El Monte, CA
4.8
2022 Lexus IS 350 350 F SPORT RWD's photo

2022 Lexus IS 350 350 F SPORT RWD

30,198 mi.

6 days on market

JTHGZ1B20N5055016

$47,795
Fair Deal
Crown Toyota
Ontario, CA
4.6
2005 Lexus IS 350 300's photo

2005 Lexus IS 350 300

152,162 mi.

6 days on market

JTHBD192X50095471

$6,995
Good Deal
Automania
South Gate, CA
5.0
2025 Lexus IS 350 350 F SPORT RWD's photo

2025 Lexus IS 350 350 F SPORT RWD

18,575 mi.

6 days on market

JTHGZ1B27S5085173

$48,040
Good Deal
Lexus San Diego
San Diego, CA
4.7
2007 Lexus IS 350 250 6AT's photo

2007 Lexus IS 350 250 6AT

140,034 mi.

6 days on market

JTHBK262272025289

$9,999
Fair Deal
Smart Motors
Ontario, CA
5.0
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

29,300 mi.

6 days on market

JTHDA1D24P5127426

$37,585
Fair Deal
Lexus Santa Monica
Santa Monica, CA
4.7
2017 Lexus IS 350 200t's photo

2017 Lexus IS 350 200t

105,692 mi.

6 days on market

JTHBA1D20H5057190

$17,499
Great Deal
Baldwin Auto Sales
Escondido, CA
3.3
2017 Lexus IS 350 200t's photo

2017 Lexus IS 350 200t

50,964 mi.

6 days on market

JTHBA1D23H5044885

$25,966
Fair Deal
Mercedes Benz Of Laguna Niguel
Laguna Niguel, CA
4.6
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

28,177 mi.

6 days on market

JTHGZ1B25P5068914

$45,785
Fair DealClean title
Northridge Toyota
Los Angeles, CA
4.3
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

66,146 mi.

6 days on market

JTHGZ1B27P5064007

$39,750
Good DealSingle owner
Plug In Auto
West Covina, CA
3.1
2022 Lexus IS 350 350 F SPORT RWD's photo

2022 Lexus IS 350 350 F SPORT RWD

37,118 mi.

7 days on market

JTHGZ1B22N5056538

$42,500
Fair Deal
Ford Of Long Beach
Long Beach, CA
4.2
2015 Lexus IS 350 250's photo

2015 Lexus IS 350 250

62,806 mi.

7 days on market

JTHBF1D27F5062871

$21,990
Fair DealClean title
Lexus Of Las Vegas
Las Vegas, NV
4.7
2007 Lexus IS 350 250 6AT's photo

2007 Lexus IS 350 250 6AT

145,575 mi.

7 days on market

JTHBK262175028540

$8,400
Good Deal
Alonsos Auto Group
Oxnard, CA
5.0
2022 Lexus IS 350 300 RWD's photo

2022 Lexus IS 350 300 RWD

36,003 mi.

7 days on market

JTHDA1D28N5121531

Contact Dealer
Single owner
Frontier Toyota
Santa Clarita, CA
4.6
2018 Lexus IS 350 300 F SPORT AWD's photo

2018 Lexus IS 350 300 F SPORT AWD

104,410 mi.

7 days on market

JTHC81D26J5031831

$22,493
Good Deal
Autonation Honda Costa Mesa
Costa Mesa, CA
4.6
2024 Lexus IS 350 300 AWD's photo

2024 Lexus IS 350 300 AWD

24,154 mi.

7 days on market

JTHB81F20R5053134

$42,900
Fair Deal
Bmw Of Murrieta
Murrieta, CA
4.6
2013 Lexus IS 350 250C 6ECTi's photo

2013 Lexus IS 350 250C 6ECTi

103,518 mi.

7 days on market

JTHFF2C27D2529133

$12,998
Great Deal
Hi Auto Sales Inc
Westminster, CA
3.9
2008 Lexus IS 350 250 6AT's photo

2008 Lexus IS 350 250 6AT

102,167 mi.

7 days on market

JTHBK262382081226

$15,988
Fair Deal
Norwalk Toyota
Norwalk, CA
4.2
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

13,242 mi.

7 days on market

JTHGZ1B27P5065769

$46,486
Fair Deal
Lexus Carlsbad
Carlsbad, CA
4.6
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

26,417 mi.

7 days on market

JTHCA1D23P5128272

$36,885
Good Deal
Sunrise Ford North Hollywood
Los Angeles, CA
4.1
2026 Lexus IS 350 350 F SPORT AWD's photo

2026 Lexus IS 350 350 F SPORT AWD

10,429 mi.

7 days on market

JTHGZ1E24T5045940

$51,390
Good Deal
Keyes Lexus
Los Angeles, CA
4.5
2019 Lexus IS 350 300 F SPORT RWD's photo

2019 Lexus IS 350 300 F SPORT RWD

135,472 mi.

7 days on market

JTHBA1D23K5093320

$20,995
Good Deal
Deluxe Auto
Midway City, CA
3.2
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

12,493 mi.

8 days on market

JTHDA1D23P5123898

$39,525
Fair Deal
Lexus Santa Monica
Santa Monica, CA
4.7
2021 Lexus IS 350 300 RWD's photo

2021 Lexus IS 350 300 RWD

48,094 mi.

8 days on market

JTHCA1D27M5110210

$29,684
Good Deal
W I Simonson
Santa Monica, CA
4.6

Showing 85 - 112 from 525 results

Find Used Lexus IS 350 in Santee, CA

In the U.S., the Lexus IS 350 is available as Convertible, Sedan, and Wagon. The best choice typically depends on space needs and personal preference.