525 Used Lexus Is-350 for Sale Near Santee, CA

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lexus
Model: is-350
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2007 Lexus IS 350 250 AWD's photo

2007 Lexus IS 350 250 AWD

84,942 mi.

16 days on market

JTHCK262372012362

$13,995
Fair Deal
Luxury Motors Credit Inc
Bridgeview, IL
2015 Lexus IS 350 250's photo

2015 Lexus IS 350 250

141,598 mi.

27 days on market

JTHBF1D20F5048472

$11,950
Fair Deal
Johnnys Motors Inc
Fontana, CA
3.6
2020 Lexus IS 350 300 F SPORT BLACK LINE RWD's photo

2020 Lexus IS 350 300 F SPORT BLACK LINE RWD

79,279 mi.

27 days on market

JTHGA1D22L5104590

$28,080
Fair Deal
Newport Lexus
Newport Beach, CA
4.8

Photos coming soon

2019 Lexus IS 350 300 RWD

27 days on market

JTHBA1D25K5087907

Contact Dealer
Premium Autos El Monte
South El Monte, CA
2.8
2020 Lexus IS 350 300 F SPORT BLACK LINE RWD's photo

2020 Lexus IS 350 300 F SPORT BLACK LINE RWD

44,920 mi.

28 days on market

JTHGA1D25L5103448

$29,699
Fair Deal
Space Auto Group Inc
Los Angeles, CA
4.4
2021 Lexus IS 350 350 F SPORT RWD's photo

2021 Lexus IS 350 350 F SPORT RWD

67,777 mi.

28 days on market

JTHGZ1B24M5043482

$41,988
Fair Deal
Norwalk Toyota
Norwalk, CA
4.2
2017 Lexus IS 350 350's photo

2017 Lexus IS 350 350

116,519 mi.

28 days on market

JTHBE1D2XH5029319

$23,084
Good Deal
Citrus Motors Ford
Ontario, CA
4.6
2015 Lexus IS 350 250's photo

2015 Lexus IS 350 250

88,220 mi.

28 days on market

JTHBF1D21F5066804

$18,995
Fair Deal
Drive Today Auto
Los Angeles, CA
5.0
2025 Lexus IS 350 300 F SPORT DESIGN RWD's photo

2025 Lexus IS 350 300 F SPORT DESIGN RWD

1,246 mi.

28 days on market

JTHBA1D26S5134989

$44,988
Fair Deal
Lexus Of Woodland Hills
Los Angeles, CA
4.8
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

18,241 mi.

28 days on market

JTHGZ1B25P5067214

$46,605
Fair Deal
Lexus Of Cerritos
Cerritos, CA
4.5
2017 Lexus IS 350 200t's photo

2017 Lexus IS 350 200t

125,344 mi.

28 days on market

JTHBA1D29H5054868

$18,387
Good Deal
All In Auto Group
Norco, CA
3.0
2024 Lexus IS 350 350 F SPORT RWD's photo

2024 Lexus IS 350 350 F SPORT RWD

25,644 mi.

29 days on market

JTHGZ1B27R5079755

$43,977
Great Deal
Mercedes Benz Of Beverly Hills
Beverly Hills, CA
4.6
2006 Lexus IS 350 250 6AT's photo

2006 Lexus IS 350 250 6AT

134,600 mi.

29 days on market

JTHBK262565002165

$6,995
Good Deal
Los Angeles Car Club Llc
Pasadena, CA
4.2
2025 Lexus IS 350 300 F SPORT DESIGN RWD's photo

2025 Lexus IS 350 300 F SPORT DESIGN RWD

48,053 mi.

29 days on market

JTHBA1D25S5133865

$39,999
Good DealSingle owner
Diamond Mazda
Lancaster, CA
4.4
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

32,932 mi.

29 days on market

JTHGZ1B27P5066484

$43,200
Good Deal
Chino Hills Ford
Chino, CA
4.0
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

19,211 mi.

30 days on market

JTHGZ1B26P5071742

$43,455
Great Deal
Temecula Valley Lexus
Temecula, CA
4.9
2024 Lexus IS 350 300 AWD's photo

2024 Lexus IS 350 300 AWD

40,933 mi.

30 days on market

JTHB81F2XR5054355

$38,444
Good Deal
Temecula Valley Lexus
Temecula, CA
4.9
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

61,503 mi.

30 days on market

JTHGZ1B27P5061558

$39,999
Good Deal
Fontana Motors Direct
Fontana, CA
4.2
2025 Lexus IS 350 300 F SPORT DESIGN RWD's photo

2025 Lexus IS 350 300 F SPORT DESIGN RWD

8,986 mi.

30 days on market

JTHBA1D24S5134831

$46,991
Fair DealSingle ownerClean title
Dalton Toyota National City
National City, CA
4.6
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

19,253 mi.

30 days on market

JTHGZ1B2XP5069735

$44,996
Fair Deal
Temecula Valley Lexus
Temecula, CA
4.9
2015 Lexus IS 350 250's photo

2015 Lexus IS 350 250

138,019 mi.

30 days on market

JTHBF1D28F5056044

$14,995
Great DealClean title
Riverside Auto Market
Riverside, CA
4.7
2021 Lexus IS 350 350 F SPORT RWD's photo

2021 Lexus IS 350 350 F SPORT RWD

27,020 mi.

30 days on market

JTHGZ1B25M5041854

$43,640
Fair Deal
Tustin Lexus
Tustin, CA
4.6
2014 Lexus IS 350 250 6AT's photo

2014 Lexus IS 350 250 6AT

141,212 mi.

30 days on market

JTHBF1D22E5002267

$13,995
Good Deal
1st Class Auto Group Llc
Fontana, CA
5.0
2020 Lexus IS 350 300 RWD's photo

2020 Lexus IS 350 300 RWD

79,834 mi.

30 days on market

JTHAA1D21L5104280

$24,198
Great DealClean title
Valley Automall
Henderson, NV
4.0
2020 Lexus IS 350 300 RWD's photo

2020 Lexus IS 350 300 RWD

47,452 mi.

30 days on market

JTHDA1D26L5104370

$28,699
Fair Deal
California Motor Trade
Norco, CA
4.2
2025 Lexus IS 350 350 F SPORT RWD's photo

2025 Lexus IS 350 350 F SPORT RWD

13,464 mi.

30 days on market

JTHGZ1B20S5086259

$49,491
Good Deal
Lexus Of Cerritos
Cerritos, CA
4.5
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

26,235 mi.

31 days on market

JTHDA1D23P5127790

$38,388
Fair DealSingle owner
Longo Lexus
El Monte, CA
4.8
2025 Lexus IS 350 350 F SPORT RWD's photo

2025 Lexus IS 350 350 F SPORT RWD

17,877 mi.

31 days on market

JTHGZ1B24S5083154

$49,635
Good DealSingle owner
Northridge Toyota
Los Angeles, CA
4.3
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

36,777 mi.

31 days on market

JTHGZ1B28P5060015

$41,990
Great Deal
Autonation Toyota Buena Park
Buena Park, CA
4.4

Showing 281 - 308 from 525 results

Find Used Lexus IS 350 in Santee, CA

In the U.S., the Lexus IS 350 is available as Convertible, Sedan, and Wagon. The best choice typically depends on space needs and personal preference.