525 Used Lexus Is-350 for Sale Near Santee, CA

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lexus
Model: is-350
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2012 Lexus IS 350 250 AWD's photo

2012 Lexus IS 350 250 AWD

146,779 mi.

1450 days on market

JTHCF5C29C5060127

$8,997
Great DealClean title
Mbl Auto Trucks
Woodford, VA
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

6,972 mi.

35 days on market

JTHDA1D29P5126918

$39,880
Fair DealSingle owner
Tustin Lexus
Tustin, CA
4.6
2024 Lexus IS 350 300 RWD's photo

2024 Lexus IS 350 300 RWD

41,157 mi.

35 days on market

JTHCA1D2XR5129342

$36,588
Good Deal
Genesis Of South Bay
Torrance, CA
4.6
2018 Lexus IS 350 300 F SPORT RWD's photo

2018 Lexus IS 350 300 F SPORT RWD

124,123 mi.

35 days on market

JTHBA1D24J5065539

$19,995
Good Deal
Surf Motors Inc
Vista, CA
5.0
2024 Lexus IS 350 350 F SPORT AWD's photo

2024 Lexus IS 350 350 F SPORT AWD

29,368 mi.

35 days on market

JTHGZ1E24R5033876

$50,495
Fair DealSingle ownerClean title
Shottenkirk Desert Lexus
Cathedral City, CA
4.0
2022 Lexus IS 350 500 F SPORT PERFORMANCE PREMIUM RWD's photo

2022 Lexus IS 350 500 F SPORT PERFORMANCE PREMIUM RWD

59,641 mi.

36 days on market

JTHAP1D2XN5001974

$54,985
Good Deal
Autonation Chevrolet Valencia
Santa Clarita, CA
4.4
2024 Lexus IS 350 350 F SPORT RWD's photo

2024 Lexus IS 350 350 F SPORT RWD

17,040 mi.

36 days on market

JTHGZ1B29R5079160

$45,133
Good Deal
Stg Montclair
Montclair, CA
4.5
2014 Lexus IS 350 250 6AT's photo

2014 Lexus IS 350 250 6AT

91,920 mi.

36 days on market

JTHBF1D21E5018153

$17,629
Fair Deal
Lexus Carlsbad
Carlsbad, CA
4.6
2023 Lexus IS 350 300 RWD's photo

2023 Lexus IS 350 300 RWD

7,942 mi.

36 days on market

JTHDA1D21P5128050

$37,995
Fair DealSingle ownerClean title
Envision Cdjr West Covina
West Covina, CA
4.0
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

41,340 mi.

37 days on market

JTHGZ1B28P5070818

$42,081
Great Deal
Crown Lexus
Ontario, CA
4.6
2009 Lexus IS 350 250 6AT's photo

2009 Lexus IS 350 250 6AT

149,972 mi.

37 days on market

JTHBK262795105334

$8,995
Good Deal
Pallares Auto Sales
Riverside, CA
4.4
2014 Lexus IS 350 350's photo

2014 Lexus IS 350 350

168,222 mi.

37 days on market

JTHBE1D28E5001501

$16,065
Good Deal
Levant Motors
South Gate, CA
4.3
2015 Lexus IS 350 250's photo

2015 Lexus IS 350 250

112,500 mi.

37 days on market

JTHBF1D26F5081881

$13,500
Great Deal
K D Auto Llc
San Diego, CA
5.0
2006 Lexus IS 350 250 6AT's photo

2006 Lexus IS 350 250 6AT

127,526 mi.

37 days on market

JTHBK262065003224

Contact Dealer
Jn 777 Motors
Midway City, CA
5.0
2024 Lexus IS 350 350 F SPORT AWD's photo

2024 Lexus IS 350 350 F SPORT AWD

18,563 mi.

37 days on market

JTHGZ1E2XR5033428

$49,585
Fair DealClean title
Sedano Chevrolet
Santee, CA
4.8
2025 Lexus IS 350 300 F SPORT DESIGN AWD's photo

2025 Lexus IS 350 300 F SPORT DESIGN AWD

7,270 mi.

37 days on market

JTHB81F27S5055503

$47,585
Fair DealSingle ownerClean title
Van Nuys Chrysler Dodge Jeep Ram
Los Angeles, CA
4.0
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

70,808 mi.

38 days on market

JTHGZ1B21P5058722

$38,405
Good DealSingle owner
Autonation Infiniti Tustin
Tustin, CA
4.5
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

43,275 mi.

38 days on market

JTHGZ1B24P5060271

$44,910
Fair DealClean title
Honda Of Escondido
Escondido, CA
4.6
2017 Lexus IS 350 200t's photo

2017 Lexus IS 350 200t

122,557 mi.

38 days on market

JTHBA1D28H5044154

$17,975
Good Deal
Great Deals Auto Group Inc
Bloomington, CA
4.3
2024 Lexus IS 350 350 F SPORT DESIGN RWD's photo

2024 Lexus IS 350 350 F SPORT DESIGN RWD

16,257 mi.

38 days on market

JTHGZ1B26R5079178

$42,379
Great Deal
All In Auto Group
Norco, CA
3.0
2026 Lexus IS 350 350 F SPORT DESIGN RWD's photo

2026 Lexus IS 350 350 F SPORT DESIGN RWD

9 mi.

39 days on market

JTHBZ1B25T5102371

$54,465
Fair Deal
Lexus Santa Monica
Santa Monica, CA
4.7
2012 Lexus IS 350 F's photo

2012 Lexus IS 350 F

51,064 mi.

39 days on market

JTHBP5C2XC5010474

$49,999
Fair Deal
Corsa Galleria
Glendale, CA
4.9
2021 Lexus IS 350 300 RWD's photo

2021 Lexus IS 350 300 RWD

26,021 mi.

39 days on market

JTHCA1D23M5112097

$32,915
Fair Deal
Bmw Of Chula Vista
Chula Vista, CA
5.0
2024 Lexus IS 350 350 F SPORT DESIGN RWD's photo

2024 Lexus IS 350 350 F SPORT DESIGN RWD

6,482 mi.

39 days on market

JTHBZ1B25R5078548

$47,922
Fair Deal
Lexus Of Riverside
Riverside, CA
4.7
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

40,480 mi.

40 days on market

JTHGZ1B21P5067467

$41,000
Great Deal
North County Gmc
Escondido, CA
4.3
2023 Lexus IS 350 350 F SPORT RWD's photo

2023 Lexus IS 350 350 F SPORT RWD

22,831 mi.

40 days on market

JTHGZ1B21P5059367

$44,082
Good Deal
Crown Lexus
Ontario, CA
4.6
2017 Lexus IS 350 200t's photo

2017 Lexus IS 350 200t

71,288 mi.

40 days on market

JTHBA1D21H5041998

$22,084
Fair Deal
Genesis Of Van Nuys
Los Angeles, CA
5.0
2015 Lexus IS 350 250's photo

2015 Lexus IS 350 250

146,116 mi.

40 days on market

JTHBF1D21F5069489

$15,495
Good Deal
J And R Motors
Riverside, CA
4.7
2014 Lexus IS 350 250 6AT's photo

2014 Lexus IS 350 250 6AT

145,700 mi.

40 days on market

JTHBF1D29E5017204

$13,335
Good Deal
S J Auto
Long Beach, CA
4.2

Showing 337 - 364 from 525 results

Find Used Lexus IS 350 in Santee, CA

In the U.S., the Lexus IS 350 is available as Convertible, Sedan, and Wagon. The best choice typically depends on space needs and personal preference.